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DNA双链断裂修复基因多态与肺癌易感性研究进展 被引量：1

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摘要 DNA双链断裂(double-strand breaks,DSBs)是最严重的DNA损伤,可导致基因组不稳定和肿瘤。DNA双链断裂修复基因多态性能改变DNA损伤的修复能力,影响肺癌的易感性。本文就xrcc2、xrcc3、xrcc4、rad,brca1和brca2基因的结构、功能和与肺癌的易感性关系作一综述。
作者 何斐 蔡琳
机构地区 福建医科大学公共卫生学院流行病与卫生统计学系
出处 《中国预防医学杂志》 CAS 2010年第2期211-214,共4页 Chinese Preventive Medicine
基金 国家自然科学基金(30771845) 福建省科技开发计划资助项目(2005D075) 福建省教育厅科技项目(01601065)
关键词 肺癌 DNA双链断裂 基因多态
分类号 R734.2 [医药卫生—肿瘤]
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同被引文献14

  • 1周敏,戎霞君,高蓓莉,丁永杰,万欢英.着色性干皮病基因组D和胞苷脱氨酶基因单核苷酸多态性与肺癌易感性的关系[J].上海交通大学学报（医学版）,2011,31(10):1403-1408. 被引量：6
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中国预防医学杂志
2010年 第2期

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