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组蛋白脱乙酰基酶抑制剂抗肿瘤机制及其临床意义的研究进展 被引量：3

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作者 耿广勇 汤志刚
机构地区 安徽医科大学附属省立医院普外科
出处 《肝胆外科杂志》 2010年第1期66-69,共4页 Journal of Hepatobiliary Surgery
基金 安徽省教育厅自然科学研究项目(KJ2008B066)
关键词 组蛋白脱乙酰基酶抑制剂 肿瘤 临床意义
分类号 R730.5 [医药卫生—肿瘤]
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参考文献43

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  • 2Khochbin S, Verdel A, Lemercier C, et al. Fuaetional significance af histone deacetylase diversity. Curr Opin Genet Dev,2001,11 (2) : 162 - 166.
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  • 5Gray SG,Qian CN,Furge K,et al. Microarmy profiling of the effects of histone deacetylase inhibitors on gene expression in cancer cell lines. Int J Oncol,2004,24(4) :773 -795.
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  • 9Ouwehand K, de Ruijter A J, van Bree C, et al. Histone deacetylase inhibitor BL1521 induces a Gl-phase arrest in neuroblastoma cells through altered expression of cell cycle proteins. FEBS Lett,2005,579 (6) :1523 - 1528.
  • 10Fang JY. Histone deaeetylase inhibitors, antieaneerous mechanism and therapy for gastrointestinal cancers. J Gastroenterol Hepatol, 2005,20 (7) :988 - 994.

同被引文献82

  • 1李晓晖,李建勋,李世荣,修志龙,西野宪和.环肽类组蛋白去乙酰化酶抑制剂[J].化学进展,2007,19(5):762-768. 被引量：7
  • 2Dokmanovic M,Clarke C,Marks PA.Histone deacetylase in hibitors:overview and perpectives[J].Mol Cancer Res,2007,5(10):981-989.
  • 3Vigushin DM,Coombes RC.Histone deacetylase inhibitors in cancer treatment[J].Anticancer Drugs,2002,13(1):1-13.
  • 4Witt O,Deubzer HE,Milde T,et al.HDAC family:what are the cancer relevant targets[J]? Cancer Letters,2009,277:8-21.
  • 5RosatoRR,Maqqio SC,Almenara JA,et al.The histone deacety-lase inhibitor LAQ824 induces human leukemia cell death thmugha process involving XIAP down-regulation,oxidative injury,and the acid sphingomy-elinase-dependent generation of ceramide[J].Mol Pharmacol,2006,69(1):216-225.
  • 6Kim S,Kang JK,Kim YK,et al.Histone deacetylase inhibitor api-cidin induces cyclin E expression through Sp1 sites[J].Biochem Biophys Res Commun,2006,342(4):1168-1173.
  • 7Archer SY,Meng S,Shei A,et al.p21(WAF1) is required for buty-rate-mediated growth inhibition of human colon cancer cells[J].Proc Natl Acad Sci USA,1998,95(12):6791-6796.
  • 8Ouwehand K,deRuijter AJ,van Bree C,et al.Histone deacetylase in-hibitor BL1521 induces a G1-phase arrest in neuroblastoma cells through altered expression of cell cycle proteins[J].FEBS Lett,2005,579(6):1523-1528.
  • 9Fang JY.Histone deacetylase inhibitors,anticancerous mechanism and therapy for gastrointestinal cancers[J].J Gastroenterol Hepato,2005,20(7):988-994.
  • 10Sakajiri S,Kumagai T,Kawamata N,et al.Histone deacetylase inhibi-tors profoundly decrease proliferation of human lymphoid cancer cell lines[J].Exp Hemato,2005,33(1):53-61.

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肝胆外科杂志
2010年 第1期

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