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吗啡戒断对糖水条件性位置偏爱建立的影响 被引量：2

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摘要 长期滥用成瘾物质使中脑边缘多巴胺能通路发生适应性蓬化，对自然奖赏物的反应性降低，阿片类滥用者性欲和食次下降、社交退缩均是这种现象的反映。只有滥用物质才能激舌已经发生适应性改变的奖赏中枢，这可能是复发的重要因。既往研究显示，苯丙胺类兴奋剂戒断后，大鼠对自然强化勿的觅求动机下降，而阿片类戒断对自然奖赏物质的觅求动机有何影响，目前尚缺乏相关研究。
作者 张登科 张宏卫 石富娟 苏巧荣 刘学红 张剑
机构地区 绍兴文理学院医学院精神病学教研室
出处 《中华行为医学与脑科学杂志》 CAS CSCD 北大核心 2010年第2期116-117,共2页 Chinese Journal of Behavioral Medicine and Brain Science
基金 国家自然科学基金资助项目（30800360） 绍兴文理学院校级课题（08LG1017）
关键词 吗啡戒断 条件性位置偏爱 苯丙胺类兴奋剂 适应性改变 糖水 多巴胺能通路 阿片类滥用者 成瘾物质
分类号 R749.6 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献11

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共引文献9

同被引文献30

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中华行为医学与脑科学杂志
2010年 第2期

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