姜的化学成分研究

Chemical constituents of rhizomes of Zingiber officinale

目的:对姜科姜属植物姜Zingiber officinale根状茎的化学成分进行分离和鉴定。方法:采用硅胶、Sephadex LH-20等柱色谱方法对化学成分进行分离和纯化,根据其理化性质及波谱数据鉴定结构。结果:分离鉴定了9个化合物,分别为β-谷甾醇棕榈酸酯(β-sitosterol palmitate,1),异香草醛(isovanillin,2),棕榈酸乙二醇单酯,(glycol monopalmitate,3),二十六烷酸单甘油酯(hexacosanoic acid 2,3-dihydroxypropyl ester,4),马来酸酰亚胺-5-肟(maleimide-5-oxime,5),对羟基苯甲醛(p-hydroxybenzaldehyde,6),腺嘌呤(adenine,7),6-姜酚(6-gingerol,8),6-姜烯酚(6-shogaol,9),和1个组合物1-(ω-ferulyloxycera-tyl)glycerols(10a^10f),结论:化合物1~7,10a^10e是首次从该植物中分离得到,1-(30-ferulyloxytriaconatanoyl)glycerol(10f)是新化合物。

Objective ： To investigate the chemical constituents from the rhizomes of Zingiber officinale. Method ： Isolation and purification of the chemical constituents were carried out on the column chromatography of silica gel and Sephadex LH-20. The structures were elucidated on basis of physicochemical properties and spectral data. Result： Ten compounds were isolated and identified as β-sitosterol palmitate （ 1 ） , isovanillin （ 2 ）, glycol monopalmitate （ 3 ） , hexacosanoic acid 2,3-dihydroxypropyl ester （ 4 ）, maleimide-5-oxime （ 5 ） ,p-hydroxybenzaldehyde （ 6 ）, adenine （ 7 ）, 6-gingerol （ 8 ） ,6-shogaol （ 9）, and 1 - （to-ferulyloxyceratyl） glycerols （ 10a-10f）. Conclusion： Compounds 1-7 and 10a-10e are obtained from Z. officinale for the first time, and compound 10f is a new compound.