呼出气冷凝液检测在儿童哮喘诊治中的应用

Application of Exhaled Breath Condensate Detection in Diagnosis and Treatment with Childhood Asthma

呼出气冷凝液(EBC)检测技术是目前诊断、评估肺部疾病新的检测方法。EBC是通过收集呼吸道上皮细胞表面覆盖的液体,这是一种非侵入性、操作简单、重复性较好的方法,适合在婴幼儿及儿童哮喘病情评估中使用。哮喘患儿呼吸道炎症或损伤时,EBC pH值、炎性介质、细胞因子等也会随之发生相应的变化,这些炎性标志物变化可作为诊断、评估儿童哮喘的病情和疗效的良好指标。

Exhaled breath condensate （EBC） is a new method for diagnosis and evaluation of lung disease, EBC compositions form to the fluid lining airway surfaces. EBC examination is a safe, non - invasive, easy and simple diagnostic method that is suitable for applicable in infants and childhood. Changes of EBC composition occurs in the airway inflammation or injury. There are changes in the pH value, inflammatory mediators,cytokines and other composition in EBC of childhood asthma. Analysis of EBC composition can contribute to diagnosis and severity assessment of childhood asthma.