1Melcangi RC, Garcia-Segura LM, Mensah-Nyagan AG. Neuroactive steroids: state of the art and new perspectives. Cell Mol Life Sci, 2008,65 : 777-797.
2Lieberman S, Kaushik G. Other conceivable renditions of some of the oxidative processes used in the biosynthesis of steroid hormones. J Steroid Biochem Mol Biol, 2006,101: 31- 41.
3Hojo Y,Hattori T,Enami T,et al. Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017alpha and 17450 aromatase localized in neurons. Proc Natl Acad Sci USA, 2004, 101 : 865-870.
4Rego JLD, Seong JY, Burel D, et al. Neurosteroids biosynthesis: Enzymatic pathways and neuroendocrine regulation by neurotransmitters and neuropeptids. Front Neuroendocrinol, 2009,30:259-301.
5Tomy S,Wu GC, Huang HR,et al. Developmental expression of key steroidogenic enzymes in the brain of protandrous black porgy fish, Acanthopagrus sehlegeli. J Neuroendocrinol, 2007, 19:643-655.
6Aste N, Watanabe Y, Shimada K, et al. Sex- and age-related variation in neurosteroidogenic enzyme mRNA levels during quail embryonic development. Brain Res, 2008,1201 : 15-22.
7George O,Vallee M,Le Moal M,et al. Neurosteroids and cholinergic systems:implications for sleep and cognitive processes and potential role of age-related changes. Psychopharmacology, 2006,186 : 402-413.
8Schilebs R,Arendt T. The significance of the cholinergic system in the brain during aging and Alzheimer's disease. J Neural Transm, 2006,113 : 1625-1644.
9Ping SE, Trieu J, Wlodek ME, et al. Effects of estrogen on basal forebrain cholinergie neurons and spatial learning. J Neurosci Res, 2008,86 : 1588-1598.
