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特发性血小板减少性紫癜发病机制研究进展 被引量:27

Study Progress of Pathogenesis of Idiopathic Thrombocytopenic Purpura
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摘要 特发性血小板减少性紫癜是一种获得性的自身免疫性疾病,其特征是针对血小板膜表面糖蛋白,特别是针对糖蛋白Ⅱb/Ⅲa和糖蛋白Ⅰb/Ⅸ复合物的自身抗体在单核巨噬细胞系统被清除所导致的血小板减少和紫癜。其发病机制尚未完全明确,目前认为是体液免疫、细胞免疫、巨核细胞等的调控异常和人类白细胞抗原遗传多态性等多方面综合作用的结果。
出处 《实用儿科临床杂志》 CAS CSCD 北大核心 2010年第3期157-159,共3页 Journal of Applied Clinical Pediatrics
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