火焰原子吸收法测定可乐宝林片中锌的含量

Determination the content of zinc in KeLeBaoLin (clonidine hydrochloride and zinc gluconate) tablets by flame atomic absorption spectrometry

目的:建立可乐宝林片中锌含量的测定方法。方法:供试品加盐酸超声处理,采用火焰原子吸收分光光度法测定。结果:该方法的线性、精密度、准确度等均良好,锌的线性良好(r=0.999 8),平均回收率为97.6%(RSD为1.17%)(n=9)。结论:本方法灵敏度高、准确可靠,可作为可乐宝林片中锌的含量测定方法。

OBJECTIVE To establish a flame atomic absorption spectrometry（FAAS）method for determination of the con tent of zinc in KeLeBaoLin （clonidine hydrochloride and zinc gluconate） tablets. METHODS The sample was extracted under uhrasonication with hydrochloric acid（0. 5→100 mL）. FAAS method was used to determine the content of zinc. RESULTS A good linearity of zinc was obtained（r = 0. 999 8）. The average recovery of zinc was 97. 6 % （RSD 1.17% ） （n = 9）. CONCLU- SION The metbod is simple,accurate and rapid,it can be used for quality control of zinc in KeLeBaoLin （clonidine hydroehloride and zinc gluconate） tablets.