炎琥宁治疗小儿急性上呼吸道感染的应用

Study on the therapeutic effect of potassium sodium dehydroandrographolide succinate on children's acute respiratory tract infection

目的:探讨炎琥宁治疗小儿急性呼吸道感染中的效果和价值。方法:将96例小儿急性呼吸道感染随机分为2组,观察组50例,对症治疗后给予静脉滴注炎琥宁,10mg.kg-1.d-1,每天1～2次,3～5d为1个疗程;对照组46例,对症治疗后给予静脉滴注利巴韦林10～15mg.kg-1.d-1,qd,3～5d为1个疗程;观察2组患儿的发热、咳嗽、流涕、喷嚏、喘气和临床治疗效果。结果:观察组治疗总有效率为96.00%(48/50),对照组为82.61%(38/46),2组比较差异有显著性(P<0.05)。结论:炎琥宁治疗小儿急性上呼吸道感染,可显著缩短病程及缓解症状,安全有效。

OBJECTIVE To explore the clinical curative effect and the value of potassium sodium dehydroandrographolide suceinate on children＇s acute respiratory tract infection. METHODS 96 children with acute respiratory tract infection were divided randomly into two groups. The intervention group （50 cases） was treated with potassium sodium dehydroandrographolide succinate, 10 mg·kg^-1·d^-1 ,once to twice daily, three to five days for one period of treatment;The control group （46 cases） was treated with phleboclysis ribavirin 10 to 15mg·kg^-1·d^-1 ,once daily, three to five days for one period of treatment. Then the changes in the symptoms （fever, cough, snivel, sneeze, puff, blow） and the effects of the treatment of the two groups patients were observed. RESULTS Total effective rate of the intervention group was 96.00% （48/50） and it was 82.61% （38/ 46） in the control group, there were significant differences between two groups（P〈0. 05）. CONCLUSION Potassium sodium dehydroandrographolide succinate used for children＇s acute respiratory tract infection can measurably shorten the course of disease, relief symptom, and shows evident effective and high safe.