两种方案治疗慢性荨麻疹的成本-效果分析

Two Therapeutic Schemes for Chronic Urticaria:Cost-Effectiveness Analysis

目的:比较氯雷他定和氯马斯汀两种方案治疗慢性荨麻疹的经济效果。方法:采用药物经济学原理对两种治疗方案进行成本-效果分析。结果:氯雷他定组和氯马斯汀组治疗慢性荨麻疹第28天的有效率分别为93.8%、91.5%,两组间无显著性差异(P>0.05);成本-效果比(C/E)分别为3.81、3.47。与氯马斯汀组相比,氯雷他定组每增加一个单位效果需多花费17.2元。结论:两种方案治疗慢性荨麻疹有效率无显著性差异,但氯马斯汀组成本-效果比优于氯雷他定组。

OBJECTIVE： To compare the cost-effectiveness between loratadine and clemastine in the treatment of chronic urticaria.METHODS： The cost-effectiveness of the 2 treatment schemes was evaluated by using the principle of pharmacoeconomics.RESULTS： The effective rates of loratadine and clemastine in for chronic urticaria were 93.8% and 91.5%,respectively（P0.05）,and their cost-effectiveness ratios（C/E） were 3.81 and 3.47,respectively.The cost for every one unit increment of effectiveness in loratadine group was 17.2 yuan higher as against clemastine group.CONCLUSION： There was no significant difference between these two schemes in clinical effective rate in the treatment of chronic urticaria,but the cost-effectiveness ratio of the clemastine is superior to that of loratadine.