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五羟色胺转运体启动子区CpG岛甲基化与精神分裂症的相关性研究 被引量：1

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摘要 本文综述了DNA甲基化及5羟色胺转运体与精神分裂症的研究进展。通过分析三者之间的相关性,指出了精神分裂症发病原因的可能研究方向。
作者 董燕 白燕 许秀峰
机构地区 昆明医学院第一附属医院
出处 《国际精神病学杂志》 2010年第1期16-19,共4页 Journal Of International Psychiatry
关键词 5-羟色胺转运体 DNA甲基化 精神分裂症
分类号 R749 [医药卫生—神经病学与精神病学]
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参考文献15

  • 1王继才,陈晓岗.难治性精神分裂症[J].国际精神病学杂志,2009,36(1):12-16. 被引量：26
  • 2Kundakovic M, Chen Y, Costa E, et al. DNA methyhransferase inhibitors coordinately induce expression of the human reelin and ghtamic acid decarboxylase 67 genes. Mol Pharmacol. 2007; 71 (3): 644-653.
  • 3Tsujita T. Possible involvement of DNA methylation in pathogenesis of mental disorders - special reference to the twin study. Seishin Shinkeigaku Zasshi, 2004 ; 106 ( 1 ) : 36-37.
  • 4Petronis A, Gottesman Ⅱ, Kan P, et al. Monozygotic twins exhibit numerous epigenetic differences: clues to twin discordance? Schizophr Bull. 2003 ; 29 ( 1 ) : 169-178.
  • 5Iwamoto K, Bundo M, Yamada K, et al. A family-based and case-control association study of SOX10 in schizophrenia. Med Genet B Neuropsychiatr Genet. 2006; 141B (5) : 477-481.
  • 6Lesch KP, Mossner R. Genetically driven variation in serotonin uptake: Is there a link to affective spectrum, neurodevelopmental, and neurode-generative disorders? Biol Psychiatry, 1998 ; 44 : 179-192.
  • 7Bradley S, Dodelzon K, Sandhu H, et al. The relationship of serotonin transporter gene polymorphisms and haplotypes to mrna transcription. Am J Med Genet. 2005; 136: 58-61.
  • 8Malhotra AK, Goldman D, Mazzanti C, et al. A functional transporter (5-HTF) Polymorphism is associated with psycho-sis in neuroleptic-free schizophrenics. Mol Psych. 1998; 3 : 328-332.
  • 9Kaiser R, Tremblay PB, Schmider J, et al. Serotonin transporter polymorphisms : No association with response to antipsychotic treatment, but associations with the schizoparanoid and residual subtypes of schizophrenia. Mol Psych. 2001 ; 6 :179-185.
  • 10Govitrapong P, Mukda S, Turakitwanakan W, et al. Platelet serotonin transporter in schizophrenic patients with and without neuroleptic treatment. Neurochemistry international, 2002; 41 (4): 209-216.

二级参考文献16

  • 1Kane J. Treatment -resistant schizophrenic patient. J Clin Psychiatry, 1996; 57 (suppl 9) : 35 -40
  • 2Lindenmayer J. Treatment refractory schizophrenia. Psychiatr Q. 2000; 71:373-384
  • 3Saito M, Yasui Frukori N, Kaneko S, et al. Clinical pharmacogenetics in the treatment of schizophrenia. Nihon Shinkei Seishin Yakurigaku Zasshi. 2005 ; 25 : 129 - 135
  • 4Zhang XY, Zhou DF, Cao LY, et al. Cortisol and cytokines in chronic and treatment -resistant patients with schizophrenia: association with psychopathology and response to antipsychotics. Neuropsychophamacology, 2005 ; 30 ( 8 ) : 1532 - 1538
  • 5Staal WG, Hulshoff PHE, Schnack HG, et al. Structural brain abnormalities in chronic schizophrenia at the extremes of the outcome spectrum. Am J Psychiatry, 2001 ; 158 (7) : 1140 - 1142
  • 6Kalla OA, honen J, Wahlstrom J, et al. Duration of untreated psychosis and its correlates in first - episode psychosis in Finland and Spain. Acta Psychiatr Scand. 2002; 106:358 - 364
  • 7Geddes J, Freemantle N, Harrison P, et al. Atypical antipsychotics in the treatment of schizophrenia: systematic overview and meta - regression analysis. BMJ. 2000; 321 (72) : 1371 - 1376
  • 8Carpenter WT, Buchanan RW. Lessons to take home from CATIE. Psychiatr Serv. 2008 ; 59 (5) : 523 - 525
  • 9McEvoy JP, Lieberman JA, Stroup TS, et al. Effectiveness of clozapine versus olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia who did not respond to prior atypical antipsychotic treatment. Am J Psychiatry, 2006; 163 (4): 600-610
  • 10Meltzer HY, Bobo WV, Roy A, et al. A randomized, double - blind comparison of clozapine and high - dose olanzapine in treatment -resistant patients with schizophrenia. J Clin Psychiatry, 2008 ; 69 (2) : 274 - 285

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国际精神病学杂志
2010年 第1期

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