MicroRNA在呼吸系统的研究进展

Development of microRNA in lung disease

MicroRNA（miRNA）是小RNA家族中新近证明的一类高度保守的、长度约为22nt、非蛋白质编码的单链小分子RNA。目前miRNA在肿瘤、遗传性疾病、心血管病、病毒感染等方面的作用得到了广泛重视，并已经开展了相关的临床研究。近年来陆续开展了一些与呼吸系统疾病相关的研究，本文就目前miRNA在呼吸系统疾病研究中的进展进行综述。

MicroRNA （miRNA） are a class of conserved highly, approximately 22 nucleotides long, non protein coding, single-stranded small molecule RNA belonging to small RNA family. The researches were focused on cancer, genetic diseases, cardiovascular diseases and viral infections, and some miRNA have been used in clinical studies. The effect of miRNA in respiratory related diseases have also attracted considerable attention in recent years. We will expatiate the scientific research of miRNA in lung disease in this article.