期刊文献+

双联抗血小板治疗并高危消化道出血的临床用药 被引量:6

Double antiplatelet therapy and high-risk of gastrointestinal bleeding in clinical medicine
下载PDF
导出
摘要 急性冠脉综合征(ACS)及经皮冠状动脉介入术(PCI)后患者应用双联抗血小板(阿司匹林+氯吡格雷)要优于单一抗血小板药物治疗。但随着阿司匹林及氯毗格雷为代表的抗血小板药物在冠状动脉疾病中的广泛应用,与该类药物相关的胃肠道损伤亦随之备受关注。
出处 《中国心血管病研究》 CAS 2010年第2期154-156,共3页 Chinese Journal of Cardiovascular Research
关键词 双联抗血小板 高危消化道出血 治疗 临床用药 Double antiplatelet High-risk of gastrointestinal bleeding Therapy Clinical medicine
  • 相关文献

参考文献16

  • 1Lewis BS, Mehta SR, Fox KA, et al.Benefit of clopidogrel according to timing of pci in patients with acute coronary syndromes:further results from the Clopidogrel in Unstable angina to prevent Recurrent Events(CURE) study. Am Heart J,2005,150:1177-1184.
  • 2Easton JD. Further perspectives for optimizing oral antiplatelet therapy. Cerebrovasc Dis, 2001,11 : 23-28.
  • 3Anderson JL, Adams CD, Antman EM, et al. ACC/AHA 2007 guidelines for the management of patients with unstable angina/ non-ST-elevation myocardial infarction. J AM Coll Cardiol, 2007,50:E1-157.
  • 4顾菲菲,柳景华.阿司匹林抵抗[J].中国心血管病研究,2005,3(3):225-229. 被引量:5
  • 5Moscucei M, Fox KA, Cannon CP, et al. Predictors of major bleeding in acute coronary syndromes: the Global Registry of Acute Coronary Events (GRACE). Eur Heart J, 2003,24 : 1815-1823.
  • 6Lai KC, Lam SK, Chu KM, et al. Lansoprazole for the prevention of recurrences of ulcer complications from long-term lowdose aspirin use. N Engl J Med,2002,346:2033-2038.
  • 7Chan FK, Cbing JY, Hung LC, et al. Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding. N Engl J Med, 2005,352 : 238-244.
  • 8Ng FH, Wong SY, Lam KF, et al. Gastrointestinal bleeding in patients receiving a combination of aspirin,clopidogrel, and enoxaparin in acute coronary syndrome. Am J Gastroenterol,2008,103: 865-871.
  • 9Anderson JL, Adams CD, Antman EM, et aI.ACC/AHA 2007 guidelines for the management of patients with unstable angina/non ST- elevation myocardial infarction:a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/non ST-elevation myocardial infarction). Circulation, 2007,116: E 148-304.
  • 10Bhatt DL, Scheiman J, Abraham NS, et al. ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet and NSAID Use:a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents. J Am Coll Cardiol,2008,52:1502-1517.

二级参考文献34

  • 1[1]Steering Committee of the Physician's Health Study of Research Group.Preliminary report:findings from the aspirin component of the ongoing physician's health study[J].N Engl J Med,1988,318(6):262-264
  • 2[2]Antithrombotic Trialists' Collaboration.Collaborative metaanalysis of randomized trials of antiplatet therapy for prevention of death,myocardial infarction,and stroke in high risk patients[J].BMJ,2002,324(7329):71-86
  • 3[3]Antiplatelet Trialists' Collaboration.Collaborative overview of randomized trials of antiplatet therapy,Ⅰ:prevention of death,myocardial infarction,and stroke by prolonged antiplatet therapy in varios categories of patients[J].BMJ,1994,308(6921):81-106
  • 4[4]Vejar M,Fragasso G,Hackett D,et al.Dissociation of platelet activation and spontaneous myocardial ischemia in unstable angina[J].Thromb Haemost,1990,63(2):163-168
  • 5[5]Hankey GJ,Eikelboom JW.Aspirin resistance[J].BM J,2004,328(7438):477-479
  • 6[6]Gum PA,Kottke-Marchant K,Poggio ED,et al.Profile and prevalence of aspirin resistance in patients with cardiovascular disease[J].Am J Cardiol,2001,88(3):230-235
  • 7[7]Grotemeyer KH.Effects of acetylsalicylic acid in stroke patients; evidence of nonresponders in a subpopulation of treated patients[J].Thromb Res,1991,63(6):587-593
  • 8[8]Mueller MR,Salat A,Stangl P,et al.Variable platet response to low-dose ASA and the risk of limb deterioration in patients submitted to peripheral arterial angioplasty[J].Thromb Haemost,1997,78(3):1003 -1007
  • 9[9]Christiaens L,Macchi L,Herpin D,et al.Resistance to aspirin in vitro at rest and during exercise in patients with angiographically proven coronary artery disease[J].Thromb Res,2002,108(2-3):115-119
  • 10[10]Sane DC,McKee SA,Malinin AI,et al.Frequence of aspirin resistance in patients with congestive heart failure treated with antecedent aspirin[J].Am J Cardiol,2002,90(8):893-895

共引文献5

同被引文献69

  • 1丽英,杨艳敏.抗血小板药物在心房颤动抗栓治疗中的应用[J].中国心脏起搏与心电生理杂志,2006,20(1):85-87. 被引量:5
  • 2Rao SV, O' Grady K, Pieper KS, et al. Impact of bleeding severity on clinical outcomes among patients with acute coronary syndromes. American Journal of Cardiology, 2005,96 : 1200-1206.
  • 3中华医学会心血管病学分会 中华心血管病杂志编辑委员会.中国不稳定型心绞痛和非sT段抬高心肌梗死诊断与治疗指南[J].中华心血管病杂志,2007,:295-304.
  • 4Chan FK, Ching JY, Hung LC, et al. Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding. N Engl J Med, 2005,352 : 238-244.
  • 5Lanas A, Seheiman J. Lowdose aspirin and upper gastrointestinal damage:epidemiology, prevention and treatment. Curt Med Res pin, 2007,23 : 163.
  • 6Manoukian SV, Feit F, Mehran R, et al. Impact of major bleed- ing on 30-day mortality and clinical outcomes in patients with a- cute coronary syndromes:an analysis from the ACUITY TriM. Journal of the American College of Cardiology,2007,49:1362- 1368.
  • 7Ng FH, Wong SY, Lam KF, et al. Gastrointestinal bleeding in patients receiving a combination of aspirin, clopidogrel, and enoxa- parin in acute coronary syndrome. Am J Gastroenterol, 2008, 103 ~ 865-871.
  • 8Ho PM, Maddox TX, Wang L, et al. Risk of adverse outcomes associated with concomitant use of inhibitors following acute coronary 937-944. clopidogrd and proton pump syndrome. JAMA,2009,301 :.
  • 9LI XQ ,ANDERSSON TB ,AHLSTR MM ,et al. Comparison of in- hibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole,pantoprazole, and rabeprazole on hu- man cytochrome P450 activities[ J]. Drug Metab Dispos ,2004,32 (8) :821 -827.
  • 10TENTZERIS I,JARAI R,FARHAN S,et al. Impact of concomi- tant treatment with proton pump inhibitors and elopidogrel onclin- ical outcome in patients after coronary steut implantation [ J ]. Thromb Haemost,2010,104(6) : 1211 - 1218.

引证文献6

二级引证文献17

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部