异构前列腺素与原发性高血压
Isoprostanes in essential hypertension
摘要
花生四烯酸产物(如前列腺素、白三烯等)的作用及意义已为我们大家所知,近年来,人们发现体内还有一些结构与前列腺素类似的物质,称为异构前列腺素(iso—PGs)。这类物质的前身也是花生四烯酸,但其形成不依赖环氧合酶,而与机体氧化应激反应产生的自由基有关,一些抗氧化剂如超氧化物歧化物、谷胱甘肽过氧化物酶和维生素E能抑制氧化损伤,并能减少其生成。因在人类正常组织及生物液体中化学性质稳定,
出处
《中国心血管病研究》
CAS
2010年第2期158-160,共3页
Chinese Journal of Cardiovascular Research
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