用于中药提取的新技术进展

Advances in new technologies applying to Chinese materia medica extraction

提取是中药制药的关键环节,影响着最终药物制剂的质量和成本,以及中药制药业的现代化水平。在简述传统中药提取技术优缺点的基础上,着重分析了近5年来中药提取新技术的基本原理、特点、研究和应用进展以及存在的问题等。这些提取技术包括:超临界萃取(SFE)、连续逆流提取(CCE)、微波萃取(MAE)、超声提取(UAE)、酶提取(ETE)、半仿生提取(SBE)、液泛提取(FE)、压榨提取(PE)、组织破碎提取(STE)、免加热提取(HFE)、空气爆破提取(AEE)、常温超高压提取(UHPE)等,并展望了中药提取技术发展的新方向。

The extraction is the key operation step in the production of Chinese materia medica or the natural products. On the basis of brief description of traditional extracting technologies, extracting techniques appeared in recent five years are particularly reviewed in the principles, features, latest research and application results, and existing problems as well. These new techniques include supercritical fluid extraction （SFE）, continuous countercurrent extraction （CCE）, microwave-assisted extraction （MAE）, ultrasound-assisted extraction （UAE）, enzymatic treatment extraction （ETE）, semi-bionic extraction （SBE）, flooding extraction （FE）, press extraction （PE）, smashing tissue extraction （STE）, heating-free extraction （HFE）, air explosion extraction （AEE）, ultra-high pressure extraction （UHPE）, etc. Further research topics and application prospects of these extracting techniques are also suggested.