南阳市15岁以下儿童艾滋病感染现状分析

Analysis on the infection situation of HIV infected children under age 15 in Nanyang city

目的了解南阳市15岁以下艾滋病感染儿童感染途径构成情况和抗病毒治疗情况,为今后防治工作提供依据。方法对南阳市艾滋病疫情网络直报数据库中年龄≤15岁的感染者资料进行分析。结果母婴传播途径感染是15岁以下儿童感染HIV的主要传播途径(占87.14%);1998年后无受血传播病例报告,2005年以后母婴传播病例逐年减少;接受抗病毒治疗者病死率(8.33%)明显低于未接受治疗者(45.45%),差异有统计学意义(P<0.005)。结论通过采取以切断血液传播和母婴传播途径为主的干预措施,儿童感染HIV病例呈逐年减少趋势,但由于女性感染者不断增多,母婴传播的隐患仍然存在,预防母婴传播仍是今后防艾工作的重点之一。抗病毒治疗可有效降低患儿病死率,应积极开展儿童的预防和治疗工作。

Objective To understand the infection route and antiretroviral therapy condition on HIV infected children under age 15 in Nanyang, and provide the basis for AIDS prevention in children. Method Epidemic surveillance database were used to analysis the information acquired from HIV infected child. Results ： Mother - to - child transmission is the main rote of HIV in children under 15. No blood transfusion ease appeared after 1998, and the number of mother - to - child transmission ease was decreasing year by year after 2005. The mortality in children who received antiretroviral therapy was lower than other＇ s, and the rate showed significant difference between them （ P 〈 0. 005 ）. Conclusion With AIDS comprehensive Intervention Measures including the prevention of blood transfusion and mother - to - child transmission, the HIV infect rate in children is decreasing. But, the prevention of mother - to - child transmission would be still a key work in future, because of the increase of female - ease. Antiretroviral therapy could decrease the AIDS mortality in child. It is another main work in future.