78例急性呼吸窘迫综合征患者的临床分析

Clinical analysis of 78 acute respiratory distress syndrome

目的分析并探讨肺内外因素所致的急性呼吸窘迫综合征有何异同点,从而为临床治疗不同病因的急性呼吸窘迫综合征提供新思路。方法收集78例急性呼吸窘迫综合征患者的临床资料并进行分组(ARDSP组和ARDSexp组),通过回顾性分析总结了两组在基础疾病、病死率、多器官功能障碍综合征的发生率、转归等方面的异同点,并对相关数据进行统计学处理。结果在APACHE-Ⅱ评分、氧合指数、住院天数、VALI的发生率等方面的差异无统计学意义。ARDSP组MODS发生率为50.00%,ARDSexp组为95.45%,后者明显高于前者,差异有统计学意义(P<0.01)。结论占急性呼吸窘迫综合征基础疾病第一位的是脓毒症,其次为肺炎、重症急性胰腺炎及中毒,肺内外因素所致的急性呼吸窘迫综合征临床所见有很多相同点,但差异性亦十分显著。

Objective To provide flesh rain of thoughts to clinical healing ARI）S by eomparing clinical features of ARDSp and ARDSexp. Methods 78 ease of ARDS were divided into 2 groups according to etiopathogenisisARDSp group and ARDSexp group, then summarize idem and disparity of the two on fundament disease,mortality rate,incidence rate of MODS and prognosis. Results There were identical in APACHE - Ⅱ score,oxygenation index, hospitalization,incidence rate of VALI. Incidence rate of MODS,mortality rate in ARDSexp group was higher than in ARDS group, and difference was obvious（ P 〈 0. 01 ）, Conclusion Maximum disease is pneumonia in ARDS group,in ARDSexp group,sepsis is most,then is severe panereatitis and poisoning. They have got a lot in common in ARDSexp group and in ARDS group, but diversity is obvious.