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低分子肝素和小剂量肝素血液透析中的抗凝作用的比较 被引量:1

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摘要 目的:比较小剂量肝素和低分子肝素在高危出血倾向患者血液透析中抗凝作用的比较。方法:比较60例出血倾向血液透析患者在透析前用小剂量肝素和低分子肝素处理后动静脉瘘穿刺点压迫所需时间、透析后透析器及管路凝血情况.并比较透析前后血小板计数、凝血酶时间(TT)。结果:低分子肝素和普通肝素均顺利完成整个透析过程。透析结束人工压迫止血时间低分子肝素明显短于普通肝素组。普通肝素透析lO例出血(5例消化道出血,2例出现皮下血肿,2例眼底出血,1例脑出血),经抢救2例脑出血死亡,其余经治疗出血停止,之后透析中应用低分子肝素抗凝。观察期间血红蛋白无明显差异,5例出现血小板减少,改为低分子肝素抗凝透析,血小板数逐渐增加。低分子肝素组未出现血小板减少及出血并发症。结论:低分子肝素较小剂量肝素用于有出血倾向患者的血液透析更具安全性。
作者 肖华
出处 《医学信息(下旬刊)》 2010年第3期43-44,共2页 Medical information
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