老年肺心病血液流变学与血气相关性分析探讨

ANALYSIS ON CORRELATION BETWEEN BLOOD RHEOLOGY AND BLOOD GAS IN SENILE PULMONARY HEART DISEASE

目的：探讨老年慢性肺心病急性发作期的血液流变学与血气分析变化关系以及复方丹参的治疗作用。方法：选择老年肺心病患者１００例和健康老人３０例，进行血液流变学检测和血气分析并对照，并观察５０例肺心病应用复方丹参治疗前后的血液流变学变化。结果：肺心病急性发作期血液均处于高粘滞状态；低氧血症与红细胞电泳率呈正相关，与全血粘度和血球压积呈负相关，酸中毒时４Φ与全血粘度呈负相关，ξΠ２与全血粘度呈正相关。结论：缺氧、酸中毒促使并加重肺心病的高粘血症；复方丹参对肺心病有改善部分血液流变学变化作用。

OBJECTIVE:To investigate correlation between blood rheological and blood gas in senile pulmonary heart disease and the therapeutic effect of compound Danshen injectio.METHODS:Blood gas and blood rheological change were analysed in 100 senile patients with pulmonary heart disease and 30 healthy elderly individuals.50 of the 100 patients were observed for rheological change before and after therapy by Danshen injectio.RESULTS:Blood of pulmonary heart disease patient was found highly sticky during its acute attack.Hypoxemia and red blood cell electrophoresis were positive correlated,but negative correlated with whole blood stickness and blood cell volume.PH value and whole blood stickness were negative correlated in case of acidosis.CONCLUSION:hypoxia and acidosis exacerbate blood stickness and compound Danshen injectio can improve rheological status in pulmonary heart disease.