摘要
目的:建立壮药排毒胶囊的质量标准。方法:用薄层色谱法鉴别处方中的何首乌、铁包金;用高效液相色谱法测定何首乌中2,3,5,4'-四羟基二苯乙烯-2-O-β-D-葡萄糖苷的含量。结果:薄层色谱鉴别特征斑点明显,阴性样品无干扰。含量测定中2,3,5,4'-四羟基二苯乙烯-2-O-β-D-葡萄糖苷在0.99~9.91μg的范围内呈良好的线性关系。平均加样回收率为100.5%,RSD=1.92%。结论:所建立的薄层色谱鉴别和含量测定方法专属性强,重复性好,可用于壮药排毒胶囊的质量控制。
Objective: To establish the quality standard for zhuang drug paidu capsules. Method: Polygoni multiflori Thunb and Berchemia lineate were identified by TLC;the content of 2,3,5,4′-tetrabydroxy-stilbene-2-O-β-D-glucoside was determined by HPLC. Result: The spots in the TLC were clear and distinguished well. the linear range of 2,3,5,4′-tetrabydroxy-stilbene-2-O-β-D-glueoside was 0. 99-9. 91μg. The average recovery was 100. 5% , RSD = 1.92%. Conclusion: The method is specific, reproducible, it can be used for quality control of Zhuang drug paidu capsules.
出处
《中国药师》
CAS
2010年第3期315-317,共3页
China Pharmacist
基金
国家科技支撑计划(编号:2006BAI06A17-02)
广西科学基金资助项目(编号:0991006)
武汉市民族药物现代化工程技术研究中心开放课题基金(编号2009003)