摘要
与其他荧光纳米粒子相比,荧光碳纳米颗粒不仅具有良好的生物相容性和易于表面功能化等优点,还具有发光稳定并可实现上转换荧光发射的特性,所以在生物医药领域有重要的应用价值。本文结合近年来的最新研究成果,综述了金刚石、石墨和非晶等不同结构的荧光碳纳米颗粒的制备方法及其局限性;分析了不同结构碳纳米颗粒的荧光发射特性和在生物技术中应用的优缺点;阐述了荧光碳纳米颗粒在今后研究中需要解决的问题和发展方向。
Comparing with other fluorescent nanoparticles （NPs）, fluorescent carbon NPs hold not only momentous properties such as good biocompatibility and facile surface functionalizability, but also excellent photostability and up-converting optical property. Therefore, fluorescent carbon NPs have a high potential application in life science and nanomedicine. To summarize the important results of recent studies, this review shows the synthetic methods and its corresponding limitations of fluorescent carbon NPs with different structures including diamond, graphite and non-crystalline, evaluates the fluorescent properties of carbon NPs with different structures, and their merit and challenge in biotechnology application. The important question to research and development directions for fluorescent carbon NPs in the future are described.
出处
《化学进展》
SCIE
CAS
CSCD
北大核心
2010年第2期345-351,共7页
Progress in Chemistry
基金
国家青年科学基金(No.50902126)
山西省青年科技研究基金(No.2009021027)
高等学校博士学科点专项科研基金(No.200800560050)
中北大学高层次人才引进启动基金(No.20080302)
中北大学重点实验室青年基金资助
关键词
荧光
碳纳米颗粒
生物相容性
纳米金刚石
fluorescence
carbon nanoparticles
biocompatibility
nanodiamond
