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β-内酰胺类及其复合制剂抗生素后效应研究进展 被引量:1

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摘要 1944年Bigger观察到抗生素移除后细菌延迟生长的现象,趔后始终未引起重视,直到20世纪70年代中期,抗生素后效应(post antibiotic effect,PAE)这一概念才被正式提出。1977年McDonald等。提出PAE是指细菌与浓度高于最小抑菌浓度(MIC)的抗生素短暂接触,清除药物后,细菌生长仍受到持续抑制的效应。1992年Odenhoh—Tornqvist等提出亚抑菌浓度抗生素后效应(post antibiotic sub—MIC effect,PASME),
作者 吴巧稚 王霆
出处 《药物流行病学杂志》 CAS 2010年第3期160-163,共4页 Chinese Journal of Pharmacoepidemiology
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同被引文献40

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