消渴通络丸在2型糖尿病周围血管病变中的临床研究

Therapeutic effect of Xiaoke tongluo pills in treating peripheral angiopathy in patients with Type 2 diabetes mellitus

[目的]探讨消渴通络丸治疗2型糖尿病周围血管病变中的作用。[方法]将42例患者随机分为治疗组与对照组,治疗组22例,对照组20例。治疗组用消渴通络丸治疗,对照组单用培达(西洛他唑)治疗。[结果]两组患者治疗后,对照组总有效率为70%,治疗组为95.5%,两组患者总有效率比较,治疗组明显优于对照组(P<0.05)。两组患者治疗前后临床症状评分及中医证候积分比较,有显著性差异(P<0.05)。[结论]消渴通络丸治疗2型糖尿病血管病变较用培达(西洛他唑)有更明显的效果,值得临床推广。

[Objective] To observe the curative effect of Xiaoke tongluo pills in treating peripheral angiopathy in patients with Type 2 diabetes. [Methods] Forty patients with Type 2 diabetes were randomly divided into treatment group and control group. Twenty-two patients in treatment group were treated with Xiaoke Tongluo pills and those in control group with Pletaal alone. [Results] The total effective rate was 95.5% in the treatment group and 70% in the control group. Compared to control group, the effect of treatment group had obviously difference（P〈0.05）. Compared to control group, there was a significant difference in the score of clinical symptom and the evaluation of TCM symptom before and after treatment. [Conclusion] Xiaoke tongluo pills had more obvious curative effect than Pletaal alone in treating peripheral angiopathy in patients with type 2 diabetes mellitus and deserved for clinical extension.