辣椒素发酵产物对小鼠营养性肥胖的预防作用

Prevention of nutritional obesity in mouse by capsaicin fermentation products

目的:研究辣椒素发酵产物对小鼠营养性肥胖的预防效果。方法:小鼠始终饲喂高脂饲料,并以灌胃方式给药,观测体重、Lee’s指数、脂肪组织湿重、脂肪细胞数目和大小及血清总胆固醇和甘油三酯等指标。结果:除血糖外给药组小鼠各项指标与对照组相比均有统计学差异。结论:辣椒素发酵产物对小鼠营养性肥胖有预防作用。

Objective.To study the preventing obesity action of nutritional obesity in mouse by capsaicin fermentation products.Methods. Mice were fed with high-fat diet all the time and capsaicin fermentation products were administered by gastric gavage.Then,weight, Lee＇ s index, wet weight of fat, quantity and size of adipose cell in the same visual field and blood index were measured.Results： Except for blood glucose, there were significant difference between experimental group and control groups.Conclusion. Capsaicin fermentation products have preventing obesity action of nutritional obesity in mouse.