摘要
In this paper,the 99mTc-octreotide scintimammography as a useful complementary technique of mammography was evaluated in diagnosing breast cancers.The 45 breast lesions were consecutively detected by mammography,and 99mTc-octreotide scintimammography,and both combination technique on the basis of self-examination,physical examination.Clinical diagnosis was confirmed by histopathologic analysis.Radioactivity uptake ratios for tumor vs normal breast tissues (T/NT) were calculated using regions of interest.In the breast cancer groups and the benign lesion groups,the average uptake ratios of the 99mTc-octreotide were 1.63±0.19 and 1.09±0.13,respectively,and t was 9.638 (P<0.001).Based on sensitivity,specificity,accuracy,positive predicting value,and negative predicting value,99mTc-octreotide scintimammography was 87%,79%,84%,90%,and 73%,the mammography was 65%,64%,64%,80%,and 45%,and both combination was 95%,100%,97%,100% and 92%,respectively.This showed that the 99mTc-octreotide scintimammography was more useful than mammography in the evaluating suspected breast cancers,and the combination technique can accurately discriminate lesions.
In this paper, the 99mTc-octreotide scintimammography as a useful complementary technique of mammography was evaluated in diagnosing breast cancers. The 45 breast lesions were consecutively detected by mammography, and 99mTc-octreotide scintimammography, and both combination technique on the basis of self-examination, physical examination. Clinical diagnosis was confirmed by histopathologic analysis. Radioactivity uptake ratios for tumor vs normal breast tissues （T/NT） were calculated using regions of interest. In the breast cancer groups and the benign lesion groups, the average uptake ratios of the 99mTc-octreotide were 1.63±0.19 and 1.09±0.13, respectively, and t was 9.638 （P〈0.001）. Based on sensitivity, specificity, accuracy, positive predicting value, and negative predicting value, 99mTc-octreotide scintimammography was 87%, 79%, 84%, 90%, and 73%, the mammography was 65%, 64%, 64%, 80%, and 45%, and both combination was 95%, 100%, 97%, 100% and 92%, respectively. This showed that the 99mTc-octreotide scintimammography was more useful than mammography in the evaluating suspected breast cancers, and the combination technique can accurately discriminate lesions.
基金
Supported by Xiamen Municipal Health Bureau (Grant No. WSK0614)
