应变率成像技术及背向散射积分技术综合评价风湿性二尖瓣狭窄患者左心室收缩功能

Assessment of left ventrilular systolic function in patients with rheumatic mitral stenosis with strain rate imaging and integrated backscatter

目的探讨应变率成像(SRI)及背向散射积分(IBS)技术在综合评价风湿性二尖瓣狭窄(MS)患者左心室局部收缩功能中的价值。方法应用SRI及IBS技术测量30例MS患者(MS组)和30例健康志愿者(对照组)左心室各壁基底段和中间段收缩期峰值应变(Ss)、收缩期峰值应变率(SRs)及左心室心肌IBS参数。测量心脏左室整体收缩功能指标,即左心室射血分数(EF)和短轴缩短率(FS)。结果MS组左心室壁各节段Ss、SRs均小于对照组相应节段(P<0.05,P<0.01),MS组室间隔及左心室后壁心肌的IBS标准化值(IBS%)显著增大(P<0.01),IBS心动周期变异幅度(CVIB)及变异率(CVIB%)减小(P<0.01),2组间心脏左心室整体收缩功能比较差别无统计学意义(P>0.05)。结论SRI及IBS技术能够准确评价风湿性MS患者左心室局部收缩功能的变化。

Objective To research the value of strain rate imaging （SRI） and integrated backscatter （IBS）in evaluating left ventricular systolic locally function in patients with rheumatic mitral stenosis （MS）. Methods Systolic peak strain （ Ss）, systolic peak strain rate（SRs） in basal segment and middle segment of left ventricular wall and left ventricular myocardial IBS parameters were measured with SRI and IBS in 30 MS patients （ MS group） and 30 healthy volunteers （ control group）. The indexes of left vcntricular whole systolic function,ejection fraction（EF） and fraction shorting（FS） rate,were measured. Results Ss and SRs in different segments in MS group were lower than those in control group（P 〈0.05 ,P 〈 0.01 ）. IBS% in interventricular septum and left ventricular posterior wall were significantly higher（ P 〈 0.01 ）, cyclic variation of IBS（CVIB） and CVIB rate were lower（ P 〈 0.01 ）. There was no statistical significance in left ventricular whole systolic function between two groups （P 〉 0.05 ）. Conclusion SRI and IBS can evaluate correctly the changes of left ventricular regional systolic function in patients with MS.