双层聚合膜可乐定选择性涂丝电极的研究

Studies on Clonidine Hydrochloride Selective Coated Wire Electrode with Bilayer Polymeric Films

报告一种新型双层聚合膜可乐定涂丝电极的研制。通过电化学聚合,在铂丝表面修饰一层具有导电性能的聚苯胺薄膜,外层涂PVC膜(含四苯硼酸-可乐定活性物质)。此种电极既保持了涂丝电极的优点,又具备较好的稳定性和重现性,连续测定8 h,电位值漂移0.8mV,线性范围为1×10^(-1)～8×10^(-6)mol/L,电极响应斜率56.7mV/decade;用加入稀释法测定了回收率,平均回收率为100.9％,标准偏差为1.3％。

A new type of coated wire electrode (CWE) with bilayer .polymeric films is reported. Platinum wire is modified by conductive polyaniline and then with a film of PVC (containing electroactive species). This kind of electrode not only has merits of CWE, but also has fine stability and repro-ducibility. With successive determination of 8 hours, the potential drifts are about 0.8mV. The Nernstian linear range of electrode shows 1 × 10-1-8× 10-6 mol/L with an average slope of 56.7mV/decade. The direct potentiometry for samples shows 100.9% of average recovery and 1.3% of standard deviation.