期刊文献+

脑膜癌病21例临床分析 被引量:6

下载PDF
导出
摘要 目的探讨脑膜癌病(meningeal carcinomatosis,MC)的临床特征和诊断要点,以提高本病诊断水平。方法对我院2000年1月~2009年8月确诊为MC者的临床资料进行回顾性分析。结果本组21例,慢性起病11例,亚急性起病7例,急性起病3例。临床主要表现为头痛、呕吐,精神症状,癫痫发作,发作性眩晕,视力、听力下降,言语不清,肢力弱,尿便障碍等。头颅MRI增强扫描多有软脑膜强化。脑脊液压力、白细胞数及蛋白含量均增高,部分病例糖及氯化物降低,脑脊液细胞学检查均找到癌细胞。确诊为MC,其中原发病灶为肺癌12例,胃癌3例,乳腺癌、黑色素细胞瘤各2例,非霍奇金淋巴瘤及原发病灶不明各1例。结论MC临床表现无特异性,易误诊。头颅MRI增强扫描对诊断本病有重要作用,确诊依赖于脑脊液细胞学检查。
作者 曹瑾
出处 《临床误诊误治》 2010年第3期264-266,共3页 Clinical Misdiagnosis & Mistherapy
  • 相关文献

参考文献7

  • 1胡凤云 邵宏元 等.脑脊液细胞学检查对脑膜癌病的诊断价值[J].中华神经科杂志,2000,13(1):6-6.
  • 2Aparicio A, Chamberlain M C. Neoplastic meningitis[ J]. Curr Neurol Neurosci Rep, 2002,2 (3) :225-235.
  • 3关鸿志,王长华,郭玉璞,陈琳,任海涛,赵燕环.脑脊液细胞学检查的特异性发现[J].中华神经科杂志,2004,37(1):65-67. 被引量:103
  • 4Newton H B. Neurologic complications of systemic cancer [J]. Am Fam Physician, 1999,59(4) :878-886.
  • 5姜华.脑膜癌病四例误诊分析[J].临床误诊误治,2008,21(5):41-42. 被引量:1
  • 6魏士贤,徐若华,李斌,安书强.初诊为缺血性脑血管病的脑膜癌病[J].临床误诊误治,2008,21(7):59-60. 被引量:1
  • 7Balm M, Hammack J. Leptomeningeal carcinomatosis. Presenting features and prognostic factors [ J]. Arch Neurol, 1996,53(7) :626-628.

二级参考文献18

  • 1刘振亭,戚晓昆,钱海蓉,熊斌.脑膜癌病7例临床分析[J].临床神经病学杂志,2004,17(5):398-398. 被引量:3
  • 2Grossman S A,Krabak M J.Leptomeningeal carcinomatosis[J].Cancer Treat Rev,1999,25(2):103-119.
  • 3NewtonH B.Neurologic complications of systemic cancer[J].Am Fam Physician,1999,59(4):878-886.
  • 4Gerrard G E,Franks K N. Overview of the diagnosis and management of brain, spine, and meningeal metastases [J]. J Neurol Neurosurg Psychiatry ,2004,75 ( Suppl 2 ): ii37-42.
  • 5Olson M E,Chernik N L,Posner J B. Infiltration of the leptomeninges by systemic cancer. A clinical and pathologic study [J]. Arch Neurol,1974,30(2) :122-137.
  • 6Balm M,Hammack J. Leptomeningeal carcinomatosis. Presenting features and prognostic factors [ J ]. Arch Neurol, 1996,53 (7) :626-628.
  • 7Bach F,Bach F W,Pedersen A G,et al. Creatine kinase BB in the cerebrospinal fluid as a marker of CNS metastases and leptomeningeal carcinomatosis in patients with breast cancer[ J ]. Eur J Cancer Clin Oncol,1989, 25(12) :1703-1709.
  • 8Jorda M, Ganjei Azar P, Nadji M. Cytologic characteristics of meningeal carcinomatosis: increased diagnostic accuracy using carcinoembryonic antigen and epithelial membrane antigen immunocytochemistry[J]. Arch Neurol,1998.55(2) :181-184.
  • 9Grossman SA,Krabak MJ.Leptomeningeal carcinomatosis[].Cancer Treatment Reviews.1999
  • 10Prayson RA,Fischler DF.Cerebrospinal fluid cytology: an 11-year experience with 5 951 specimens[].Archives of Pathology and Laboratory Medicine.1998

共引文献124

同被引文献55

引证文献6

二级引证文献13

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部