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抗凝药物研究进展 被引量：4

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摘要 抗栓治疗主要针对凝血系统和血小板活化两个环节起作用;分别称为抗凝治疗和抗血小板治疗。目前临床抗凝药物也主要作用于这两个环节,一些新型的抗凝药物逐步用于临床或是进入临床验证阶段。本文综述了此类抗凝药物的临床研究情况,抗凝机制以及临床试验等。
作者 史旭波
机构地区 北京同仁医院心血管中心
出处 《临床药物治疗杂志》 2010年第2期9-12,共4页 Clinical Medication Journal
关键词 抗凝药物 抗凝机制 抗凝治疗
分类号 R973.2 [医药卫生—药品]
  • 相关文献

参考文献11

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同被引文献40

  • 1胡大一,孙艺红.低分子肝素与血栓栓塞性疾病[J].中华心血管病杂志,2005,33(2):198-200. 被引量：37
  • 2董建中,王鸿利.标本采集对血栓与止血实验的影响[J].上海医学检验杂志,1996,11(4):256-256. 被引量：14
  • 3程洪波,李国良,熊丽红,周桂秀,罗敏智,魏宇靖,王晓莉.影响血小板输注疗效的多因素分析[J].江西医学检验,2007,25(2):119-121. 被引量：9
  • 4Josepb J,Steven H.New oral anticoagulants:a brief review[J].Wisc Med J,2009,108(1):35-39.
  • 5Pranav Sikka,VK Bindra.Newer antithrombotic drugs[J].Indian Journal of Clinical Care Medicine,2010,14(4):188-195.
  • 6Stone GW,WARE JH,Bertrand ME,et al.Antithrombotic strategies in patients with acute coronary syndromes undergoing early invasive management:one-year results from the ACUITY trial[J].JAMA,2007,298,(21):2497-2506.
  • 7Yusuf S,Mehta SR,Chrolavicius S,et al.Effects of fondaparinux on mortality and reinfarction in patients with acute ST-segment elevation myocardial infarction:the OASIS-6R randomized trial[J].JAMA,2006,295(13):1519-1530.
  • 8Mehta SR,Yusuf S,Granger CB,et al.Design and rationale of the MICHELANGELO Organization to Assess Strategies in Acute Ischemic Syndromes(OASIS)-5 trial program evaluating fondaparinux,a synthetic factor Xa inhibitor,in patients with non-ST-segment elevation acute coronary syndromes[J].Am Heart J,2005,50(6):1107-1109.
  • 9Methta SR,Boden WE,Eikelboom JW,et al.Antithrombotic therapy with fondaparinux in relation to interventional management strategy in patients with ST-and non-ST-segment elevation acute coronary syndromes:an individual patient-level combined analysis of the Fifth and Sixth Organization to Assess strategies in Ischemic Syndromes(OASIS 5 and 6)randomized trials[J].Circulation,2008,118(20):2038-2046.
  • 10Mashio Nakamura,Yoshiaki Okano,Takeyoshi Kunieda,et al.Multidetector-row computed tomography-based clinical assessment of fondaparinux for treatment of acute pulmonary embolism and acute deep vein thrombosis in Japanese patients[J].Circ J,2011,75(6):1424-1432.

引证文献4

二级引证文献15

临床药物治疗杂志
2010年 第2期

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