呼吸内科病房院内肺部真菌感染的临床研究

Clinical Analysis of Nosocomial Pulmonary Fungal Infections in Medical Ward of Respiration

目的探讨呼吸内科病房院内肺部真菌感染的危险因素、真菌类型及治疗现状。方法对2005年1月至2008年12月期间诊断的呼吸内科病房院内肺部真菌感染患者的临床资料进行分析。结果基础疾病继发感染是肺部真菌感染的重要原因,以慢性阻塞性肺疾病多见。长期使用广谱抗生素、长期使用激素、机械通气是其主要诱因。病原菌以白色念珠菌为主,氟康唑疗效好。结论减少易感因素、早发现、早诊断、及时治疗是减少院内肺部真菌感染的有效措施。

Objective To find out the risk factors,types of fungal infection,treatment of nosocomial pulmonary fungal infections in medical ward of respiration. Methods Patients with nosocomial pulmonary fungal infections between January 2005 and december 2008 were analyzed.Results Pulmonary fungal infection is an important cause of the secondary infection in many diseases,COPD was the main predisposing disease.The frequent susceptible factors associated with nosocomial pulmonary fungal infection included long-erm use of antibiotics,long--term use of adrenocortical steroid, mechanical ventilation. Clinical feature was non--pecific. Candidiasis was the most, fluconazole had better clinical effects on reatment.Conclusion The effective methods to reduce nonsocomial pulmonary fungal infection in patients are reducing risk factors, early and timely treatment.