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浸润性乳腺癌中IGF-1的表达及其意义 被引量：3

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摘要 目的探讨浸润性乳腺癌中IGF-1的表达及生物学意义。方法应用免疫组化EnVision法检测62例浸润性乳腺癌组织中IGF-1蛋白的表达水平。结果腋淋巴结转移者中IGF-1阳性率高于无腋淋巴结转移者(P<0.05);组织学分级Ⅲ级者,IGF-1阳性率明显高于组织学分级Ⅰ、Ⅱ级者(P<0.01)。结论IGF-1蛋白是乳腺癌浸润和转移过程中的潜在生物学标志,其表达的检测对乳腺癌的浸润程度、转移特性有一定临床价值。
作者 戴晓晓 陈同钰
机构地区 江苏省苏州市吴中人民医院病理科
出处 《中外医疗》 2010年第7期43-44,共2页 China & Foreign Medical Treatment
关键词 IGF-1 乳腺肿瘤 免疫组化
分类号 R737.9 [医药卫生—肿瘤]
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参考文献7

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同被引文献33

  • 1章联,叶古祥,陈亚军,孙国娣.乳腺癌患者血清胰岛素样生长因子-1及结合蛋白-3的变化及意义[J].中国基层医药,2005,12(10):1307-1308. 被引量：3
  • 2Feng-ze WANG,Li SHA,Wei-ying ZHANG,Lian-ying WU,Ling QIAO,Nan LI,Xiao-dong ZHANG,Li-hong YE.Involvement of hepatitis B X-interacting protein (HBXIP) in proliferation regulation of cells[J].Acta Pharmacologica Sinica,2007,28(3):431-438. 被引量：16
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中外医疗
2010年 第7期

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