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高龄低位直肠癌保肛局部扩大切除21例治疗体会

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摘要 目的:探讨75岁及以上伴有合并症的低位直肠癌保肛手术的可行性。方法:对21例患者积极治疗合并症后在连续硬膜外麻醉下经肛门、阴道、骶尾入路,在肿瘤基底部注射氟尿嘧啶0.75 g+顺铂20 mg+丝裂霉素6 mg,使肿瘤基底部及周边隆起水肿,距肿块边缘至少1 cm连同直肠全层及肠周脂肪结缔组织一并完整切除。其中经肛门径路3例,经阴道径路7例,经骶尾径路11例。结果:切缘阳性1例,阴性20例。吻合口瘘4例,21例2个月内大便可完全自主控制。术后存活1、3、5年分别为21例、15例和10例。结论:高龄低位直肠癌经局部扩大切除术对患者的生存质量有明显提高。
出处 《蚌埠医学院学报》 CAS 2010年第3期278-280,共3页 Journal of Bengbu Medical College
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