慢性乙型肝炎患者复发相关因素研究

Recurrence in Patients with Chronic Hepatitis B-related Factors

目的:了解慢性乙型肝炎患者复发与生活事件、服药依从性及社会支持的关系,为更好地预防复发提供依据。方法:采用生活事件量表(LES)。服药依从性及社会支持评定量表(SSAS)。对160例因复发而再次入院的慢性乙型肝炎患者进行评定,并与86例首次住院且与观察组同期出院而未复发的门诊慢性乙型肝炎进行比较。结果:(1)观察组生活事件发生率、负性生活事件及负性生活事件值均高于对照组(P<0.01);(2)观察组SSAS总分,主观支持评分均低于对照组(P<0.01);(3)观察组服药依从性低于对照组(P<0.01)。结论:经常发生生活事件、服药依从性差及社会支持缺乏的慢性乙型肝炎患者容易复发。

Objective：To understand the recurrence of chronic hepatitis B patients with life events, medication compliance and the relationship between social support to better provide the basis for relapse prevention. Methods： Use life Event Scale （LES） , Medication compliance and Social Support Rating Scale （SSAS）. 160 cases were read- mitted because of recurrence of chronic hepatitis B patients were assessed. 86 cases of first-time hospitalization who were discharged with the same period in the observation group and without recurrence of chronic hepatitis B was compared. Results： （1）the observation group in the incidence of life events, negative life events and negative life events values are higher than the observation group （P〈0.0l） ; （2）Observer Group SSAS, the subjective value of the market rates are lower than the control group （P〈0.01） ;（3）medication compliance in the observation group lower than the control group （P〈0.01）. Conclusion：Patients with chronic hepatitis B who have the frequent occurrence of life events, poor medication compliance and lack of social support will recur easily.