摘要
利用盐酸甲氯芬酯与曙红Y在Clark-Lubs缓冲液(pH3.6)中相互作用而使体系褪色,建立了一种快速测定制剂中盐酸甲氯芬酯含量的新方法。该体系的最大褪色波长在506nm处,表观摩尔吸光系数为1.059×104L·mol-1·cm-1,盐酸甲氯芬酯在2～18μg/ml浓度范围内符合比耳定律。
A fast fading spectrophotometric method was established for the determination of meclofenoxate hydrochloride based on the reaction of meclofenoxate hydrochloride with eosin Y in the Clark-Lubs buffer media （pH 3.6）. The apparent molar absorptivity of complex was 1.059× 10^4 L.mol^-1.cm^-1 at 506 nm. Beer＇s law was obeyed in the range of 2 - 18 μg/ml for meclofenoxate hydrochloride.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2010年第3期213-215,共3页
Chinese Journal of Pharmaceuticals
基金
江苏省高校自然科学研究计划资助项目(No.05KJB150003)
关键词
盐酸甲氯芬酯
曙红Y
褪色反应
分光光度法
测定
meclofenoxate hydrochloride
eosin Y
fading reaction
spectrophotometric method
determination
