摘要
目的:观察研究原发性肝癌(PHC)并发胆结石发生率及其发生机理。方法:采用腹部B超和CT影像检查确定PHC患者并发胆结石。结果:并发胆结石发生率:PHC组22%(36/152)和继发性肝癌(MHC)组45%(2/44)比较有明显差异。P<0.05,PHC组和肝硬化(LC)组25%(14/56)比较无明显差异。结论:并发胆结石,PHC组远远高于MHC组。其原因可能与两组在门脉高压和肝功能损害存在明显差异有关。PHC和LC一样,由于门脉压增高一般都有胆囊壁充血水肿和通透性增加,同时,肝细胞受损,特别是胆红素升高引起胆汁中胆固醇、胆红素和磷脂比例和量发生改变,生成以胆红素为主的混合性结石。
Objective: To determine the occurrence rate of bilestone in patients with primary liver cancer(PLC). METHOD:Ultrasound and CT were used to diagnose bilestone in 158 patients with PLC as well as in 100 patients with cirrhosis or rnetastatic liver cancer (MLC ) as control group. Liver function was also detected. RESULTS: It was found that the bilest0ne positive rate in PLC group was 22%,which was significantly higher than that in MLC group(4. 5% ) (p0. 05),but not in the cirrhosis group (25% ) (p0.05). CONCLUSION:The patients with PLC were easily as sociated with bilestone. Risen bilirubin may be a highly risk factor for bilestone.
出处
《航空航天医药》
1998年第4期187-188,共2页
Aerospace Medicine