油松松针的化学成分

Chemical constituents from pine needle of Pinus Tabulaeformis Carr.

目的研究油松松针中的化学成分,为松属植物的化学分类学提供一定的依据。方法采用反复硅胶、聚酰胺、ODS、Sephadex LH-20柱色谱等方法进行分离纯化,根据理化性质和1H-NMR、13C-NMR等技术对分离得到的化合物进行结构鉴定。结果从油松松针中分离得到7个化合物,分别鉴定为(13S)-15-羟基半日花烷-8(17)-烯-19-酸[(13S)-15-hydroxylabd-8(17)-en-19-oicacid,1]、5,4′-二羟基-3,7,8-三甲氧基-6-甲基黄酮(5,4′-dihydroxy-3,7,8-trimethoxy-6-methylflavone,2)、柚皮素(naringenin,3)、芹菜素(apigenin,4)、高良姜素(galangin,5)、β-谷甾醇(β-sitosterol,6)、胡萝卜苷(paucosterol,7)。结论化合物1-3为首次从该属中分离得到,化合物4-7为首次从该植物中分离得到。

Objective To study the chemical constituents of pine needles of Pinus tabulaeformis Cart. Methods Compounds were isolated by the silica gel, ODS, Sephadex LH-20 columns, and their structures were identified by the physicochemical properties and 1H-NMR, 13C-NMR data. Results Seven compounds were obtained and identified as （13S） -15-hydroxylabd-8 （ 17 ） -en-19-oic acid （ 1 ）, 5,4＇-dihydroxy-3,7,8-trimethoxy-6-methylflavone （2）, naringenin （ 3 ）, apigenin （ 4 ）, galangin （ 5 ）, β-sitosterol （ 6 ）, paucosterol （ 7 ）. Conclusions Compounds 1-3 are obtained from Pinus Linn. for the first time, compounds 4-7 are obtained from Pinus tabulaeformis Carr. for the first time.