早产儿血浆总蛋白、肌酐和尿素氮变化及意义

THE CHANGE AND SIGNIFICANCE OF SERUM TOTAL PROTEIN、CREATININE、UREA IN PREMATURE INFANT

为探讨早产儿血浆总蛋白、肌酐和尿素氮变化与饮食及胃肠外营养支持的关系，对126例危重早产儿进行上述指标的动态监测。结果极低出生体重儿三项指标均值略低于非极低出生体重儿；混合营养组与葡萄糖营养组对比，后者血肌酐随禁食时间延长而逐渐降低，与前者相比有显著差别，血浆总蛋白和尿素氮两组差别不明显。说明在禁食早产儿中，血肌酐是监测营养状况指标之一。在肾功能正常情况下，若观察到血肌酐水平明显降低，应对其营养供给进行估价，保证所供给营养的质量。

To investigate the change of serum total protein (TP)、creatinine (CR)、urea (UR),and to evluate the relationship of diets and parenteral nutrition in premature infants, 126 patients with critical condition were measured consecutivly. The results show that the levels of TP、CR and UR were mild lower in very lowbirth weight infant (VLBWI) than those of non-VLBWI, and CR level was significantly decreased during the non-feeding period in group with monoglucose support, and,TP、CR level is one of the methods in evluating nutritional status of non-feeding premature infant. The patlents with much lowered CR level should be reassessed in nutrition supply