摘要
目的:探讨参麦注射液对老年冠状动脉粥样硬化性心脏病(冠心病)无症状心肌缺血的治疗效果。方法:随机将71例无症状心肌缺血患者分为2组,其中36例采用参麦注射液和阿斯匹林治疗者为治疗组,35例用复方丹参注射液和阿斯匹林治疗者为对照组。结果:治疗组用药前后ST段压低的次数分别为(182.0±10.1)次和(61.7±7.6)次;ST段压低持续总时间分别为(398.5±30.2)min和(80.2±20.4)min。对照组用药前后ST段压低次数分别为(180.8±12.5)次和(99.5±10.8)次;ST段压低持续总时间分别为(399.0±32.3)min和(141.7±29.5)min。治疗前后比较,2组均有非常显著性差异(P均<0.01)。2组间比较亦有显著性差异(P<0.05)。治疗期间未见任何不良反应。结论:参麦注射液的疗效优于复方丹参注射液。
Objective:To explore the efficiency of Shenmai Injection on treating asymptomatic myocardial ischemia in senile coronary heart disease (CHD).Methods:Seventyone cases of asymptomatic myocardial ischemia were divided into 2 groups:treatment group (36 cases) was treated with Shenmai Injection and aspirin;control group (35 cases) was treated with composite salvia miltiorrhiza injection and aspirin.Results:In treatment group,STsegment lower were (182 0±10 1) times and (61 7±7 6) times in pre and post therapy respectively;the total continuative time was (398 5±30 2) minutes and (80 2±20 4) minutes respectively.While in control group,STsegment lower were (180 8±12 5)times and (99 5±10 8) times in preand post therapy respectively,the total continuative time was (399 0±32 3)minutes and (141 7±29 5) minutes.Moreover,there was obvious difference between preand post therapy and between 2 groups ( P <0 01 or P <0 05 respectively),and no sideeffect was found.Conclusions:It suggested that Shenmai Injection was superior of therapeutic efficacy to composite salvia miltiorrhiza injection.It is an effective and safe drug in treatment of asymptomatic myocardial ischemia.
关键词
参麦注射液
心肌缺血
疗效
冠心病
老年人
Shenmai Injection\ \ coronary artery atherosclerotic heart disease\ \ asymptomatic myocardial ischemia\ \ composite salvia miltiorrhiza injection