甲型H1N1流感95例临床分析

Clinical analysis of 95 cases of influenza A(H1N1)

目的分析甲型H1N1流感的临床特征。方法对我院2009年7月—2009年9月收治的95例确诊为甲型H1N1流感患者的病例资料进行回顾性分析。结果昆明地区甲型H1N1流感患者常见临床表现为发热、咽痛、咳嗽、咯痰,咽部充血,白细胞数减少、中性粒细胞比例下降、淋巴细胞及单核细胞比例升高,咽拭子甲型H1N1病毒核酸阳性(100%)。未发现重症病例及严重并发症。采取口服磷酸奥司他韦、双黄连口服液、莲花清瘟胶囊等中西医结合治疗,效果较好,无死亡病例。结论昆明地区甲型H1N1流感临床表现典型,并发症少,但其传染性强,防控重点地区应放在人口密集的学校。

Objective To analyze clinical characteristics of influenza A （H 1N 1）. Methods Clinical data of 95 confirmed cases of influenza A （H1N1） treated in our hospital from July to Sept. 2009 were analyzed. Results The major clinical manifestations of the patients with influenza A （H1N1） in kunming included fever, angina, cough, expectoration, congestion of throat, decline in WBC and the percentage of neutrophilic granulocytes, an increased percentage of lymphocytes and monocytes, and throat swab specimen positive for influenza A （H 1 N 1） virus by RT-PCR. No severe cases and critical complications were found. Treatment with integrated Chinese and Western medicine, such as oral intake of oseltamivir, Shuanghuanglian oral liquid or Lianhua Qingwen Capsule was effective. No death case was found. Conclusion The patients with influenza A （H1N1）in Kunming have typical clinical manifestations with few complications. Preventive measures should be strengthened in densely populated venues such as schools due to the strong infectivity of influenza A （H 1 N 1）.