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构筑生物分子微图案的研究进展 被引量：1

Progress in Fabrication of Bio-micropatterns
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摘要 随着微加工技术的发展,在材料表面构筑功能化的纳微米级图案越来越成为关注的热点。在生物科学领域,光刻蚀、微接触印刷和蘸笔纳米平板印刷等微图案技术被广泛应用并实现了生物分子在几十纳米微区域上的固定。生物分子在微纳米区域内的成功固定大大推动了生物微分析、生物芯片、生物微器件等生物技术及相关领域的发展。本文从分析生物分子与材料表面的相互作用入手,较为系统地评述了构筑生物分子微图案的几种重要方法,并对生物分子微图案技术的发展做了展望。 As the development of micro fabrication technologies,the construction of functional micropatterns on the surfaces of materials has become one of the most important subjects of current research.In bioscience field,selective localization of biomolecules to micropatterns or defined positions is very important for the development of bioassay,biochip,biomicrodevices etc.The biopatterns with the feature size of tens nanometers,which have been prepared with photolithography,microcontact printing and dip-pen nanolithography etc,greatly promotes the development of many biotechnologies.This paper systematically reviews the above-mentioned methods by analyzing the interactions between bio-molecules and the surfaces of materials and describes the outlook of this technology at last.
作者 姚树寅 晏海英 吴仲岿 陈红
机构地区 武汉理工大学材料科学与工程学院 武汉理工大学材料复合新技术国家重点实验室
出处 《材料科学与工程学报》 CAS CSCD 北大核心 2010年第1期156-160,151,共6页 Journal of Materials Science and Engineering
基金 国家自然科学基金资助项目(90606013 107080)
关键词 生物分子微图案 光刻蚀 微接触印刷 蘸笔纳米平板印刷技术 Bio-micropatterns photolithography microcontact printing（μCP） dip-pen nanolithography（DPN）
分类号 TB383 [一般工业技术—材料科学与工程]
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参考文献36

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同被引文献11

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材料科学与工程学报
2010年 第1期

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