^(14)C标记农药杀螟松和马拉硫磷的制备

Preparation of ^(14)C -sumithion and ^(14)C-malathion

以Ba14CO3为起始原料制得14CH3OH，然后用14CH3OH与PSCl3在碱性条件下反应，再加入甲基硝基苯酚，在甲基异丁酮溶剂体系下制得14C－杀螟松，放化纯度＞95％，放射性比活度为188．7BMq／mol。14CH3OH与P2S5合成出的中间体，加顺丁烯酸二乙酯在甲苯溶剂体系中反应制成14C－马拉硫磷，放化纯度＞95％，放射性比活度为156．4MBq／mol。

The preparation of 14C-sumithion and 14C-malathion is presented in this paper.From 14C-barium carbonate, the 14C-methanol is synthesized and used to react with PSCl3. Then 3 - methanol-4nitrophenol is added solution of 2-hexamonethe to obtain 14C-sumithion. Its radiochemical purity is over 95% and the specific activity is 188.7GBq/mol. On the other hand 2-butenoic acid diaethyl ester is added in the solution of methyl bengene, after addition of malathion and P2S5 to form the terminal product 14C-palathion. Its radio chemical purity is over 95% and the specific activity is 156.4GBq/mol.