微波辐射合成水杨酸-2-乙基己酯的研究

Synthesis of 2-Ethylhexyl Salicylate under Microwave Radiation

采用微波辐射技术,以硫酸氢钠为催化剂,水杨酸与2-乙基己醇为原料,合成了水杨酸-2-乙基己酯。结果表明最佳反应条件为:水杨酸0.05 mol,酸醇摩尔比为1∶4,催化剂用量为反应物质量的6.93%,微波功率为360 W,微波辐射时间为35 min,不加带水剂,产率可达89.33%。并用折光率、红外光谱、紫外光谱、色质联用等手段对产品进行了确证。

2-Ethylhexyl salicylate was synthesized from 2-ethylhexanol and salicylic acid with sodium hydrogen sulfate as catalyst by use of microwave radiation.The experimental results showed that the optimum conditions were as follows： 0.05 mol salicylic acid was added,the molar ratio of salicylic acid to 2-ethylhexanol was 1∶4,the dosage of catalyst was 6.93wt% of the reagent,the microwave power was 360 W,the reaction time was 35 min,and no water-carrying reagent was used.Under the above conditions,the yield of 2-ethlyhexyl salicylate could reach 89.33%.The synthesized product was confirmed by refractive index,IR,UV and GC/MS.