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抗凋亡基因Mcl-1的研究进展 被引量:4

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出处 《吉林医学》 CAS 2010年第5期669-672,共4页 Jilin Medical Journal
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  • 1Kozopas KM, Yang T. MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2[ J]. PNAS,1993,90(3) :3516.
  • 2Zhuang L, Lee CS. Mcl - 1, Bcl - XL and Stat3 expression are associated with progression of melanoma whereas Bcl -2, AP -2 and MITF levels decrease during progression of melanoma [J]. Mod Pathol,2007,20(4) :416.
  • 3Bingle CD,Craig RW. Exon skipping in Mcl - 1 results in a bel- 2 homology domain 3 only gene product that promotes cell death[J]. J Biol Chem,2000,275(29) :22136.
  • 4Kim H, Rafiuddin - Shah, Mubina, et al. Hierarchical regulation of mitochondrion - dependent apoptosis by BCL - 2 subfamilies [ J ]. Nat Cell Biol,2006,8 (12 ) :1348.
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  • 6Aichberger KJ, Mayerhofer M. Identification of mcl - 1 as a BCR/ABL- dependent target in chronic myeloid leukemia (CML) :evidence for cooperative antileukemic effects of imatinib and mcl - 1 antisense oligonucleotides [ J ]. Blood, 2005,105 ( 8 ) : 3303.
  • 7Jiang CC, Lucas K. Up - regulation of Mcl - 1 is critical for survival of human melanoma ceils upon endoplasmic reticulum stress[J]. Cancer Res,2008,68(16) :6708.
  • 8Piret JP,Emmanuel M. Hypoxia - inducible factor - 1 - de- pendent overexpression of myeloid cell factor -1 protects hypoxic ceils against tertbutyl hydroperoxide - induced apoptosis[ J ]. J Biol Chem,2005 ,280(10) :9336.
  • 9Vickers ER, Ternary KA. Complex factor - serum response factor complex- regulated gene activity is required for cellular proliferation and inhibition of apoptotic cell death [ J ]. Mol Cell Biol,2004,24 ( 23 ) : 10340.
  • 10Marriott HM, Bingle CD. Dynamic changes in Mcl - 1 expression regulate macrophage viability or commitment to apoptosis during bacterial clearance[ J]. Mol Cell Biol,2005,115 (2) :359.

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