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急性冠脉综合征与循环补体C3的关系探讨 被引量:2

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摘要 目的评价各种类型急性冠脉综合征(ACS)患者补体第三组分(C3)激活的情况和补体C3激活与心肌损伤的关系。方法ACS组包括ST段抬高型心肌梗死(STEMI)30例,非ST段抬高型心肌梗死(NSTEMI)24例和不稳定型心绞痛(UA)36例。检测ACS患者和健康人血浆C3、肌红蛋白(Mb)浓度。结果STEMI组和NSTEMI组峰值C3水平高于UA组和正常对照组(P<0.05)。UA组C3水平高于正常对照组(P<0.05)。ACS患者C3水平在住院的前7d均有明显的变化(P<0.05)。ACS患者峰值C3水平与肌红蛋白呈正相关(r=0.897,P<0.05)。结论ACS患者血浆C3均明显升高。C3水平与ACS的联系提示补体C3激活与心肌坏死有关。
出处 《中西医结合心脑血管病杂志》 2010年第3期265-266,共2页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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