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恶性高热症研究进展 被引量:6

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摘要 恶性高热(malignant hyperthermia,MH)又称异常高热,是指由某些麻醉药激发的全身肌肉强烈收缩、并发体温急剧上升及进行性循环障碍的代谢亢进危象。一般认为多有恶性高热家族史,及肌肉细胞存在遗传性生理缺陷。本文对麻醉药物致MH的发病机制、诊断和临床处理作一简要综述。
出处 《西南军医》 2010年第2期325-327,共3页 Journal of Military Surgeon in Southwest China
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参考文献19

  • 1吕黄伟,王俊科.恶性高热的基因研究进展[J].国际麻醉学与复苏杂志,2007,28(5):460-463. 被引量:7
  • 2何玮,曹雅鲁.氟哌啶醇致恶性高热综合征一例[J].暨南大学学报(自然科学与医学版),2004,25(2):248-248. 被引量:4
  • 3Robinson R,Hopkins P,Carsana A,et al.Several interacting genes influence the malignant hyperthermia phenotype[J].Hum Genet,2003,112:217 -218.
  • 4Levitt RC,Olckers A,Meyers S,et al.Evidence for the localization of a malignant hyperthermia susceptibility locus (M HS 2)to human chromosome 17q[J].Genomics,1992,14:562-566.
  • 5Monnier N,Stieglitz P,Procaccio V,et al.Malignant hyperthermia susceptibility is associated with a mutation of the alpa-1 subunit of the hum an dihydr0pyridlne scensitive I type voltage dependent calci Hill channel receptor in skeletal muscle[J].Am J Hum Gener,1997,60:1316-1325.
  • 6MacI ennan DH,Phillips MS.Malignant hyperthermia[J].Science,1992,256:789 794.
  • 7Robinson RI,Anetseder MJ,Brancadoro V,et al.Recent advances in the diagnosis of malignant hyperthermia susceptibility:How confident can we be of genetic testing[J].Eur J Hum Genet,2003,11(4):342-348.
  • 8Sambuughin N,Sei Y,Gallagher KI,et al.North Americann Ilialignant hypertherm ia population:Screening of the ryanodine receptor gene and identification of novel mutation[J].Anesthesiology,2001,95:594-599.
  • 9Sei Y,Sambuughin NN,Davis EJ,et al.Malignant hyperthermia in North America[J].Anesthesiology,2004,101:824-830.
  • 10McCarthy TV,Healy JM,Heffrom JJ,et al.Localization of the malignant hyperthermia susceptibility locus to human chromosom e19q12-13.2[J].Nature,1990,343:562-564.

二级参考文献23

  • 1徐仲煌,郭向阳,罗爱伦.我国恶性高热发病概况、实验室诊断方法的建立及临床应用(上)[J].中华医学信息导报,2005,20(18):22-22. 被引量:4
  • 2林兆谦.发热疾病的诊断与病例分析[M].北京:人民卫生出版社,2002.990-992.
  • 3郑军 于国勤 见耿洪业 王少华主编.丁酰苯类[A].见耿洪业,王少华主编.实用治疗药物学[C].北京:人民卫生出版社,1997.397.
  • 4Nicole M, Renee KH,Payen JF,et al. Presence of two different genetic traits in malignant hyperthermia families: implication for genetic analysis, diagnosis, and incidence of malignant hyperthermia susceptibility. Anesthesiology, 2002, 97 : 1067-1074.
  • 5Girad T, Treves S, Voronkov E, et al. Molecular genetic testing of malignant hyperthermia susceptibility. Anesthesiology, 2004, 100: 1076- 1080.
  • 6Robison R, Hopkins P, Carsana A, et al. Several interacting genes influence the malignant hyperthermia phenotype. Hum Genet, 2003, 112: 217-218.
  • 7McCarthy TV, Quane KA, Lynch PJ. Ryanodine receptor mutations in malignant hyperthermia and central core disease. Hum Mutat, 2000, 15 : 410-417.
  • 8Feng W, Fessenden JD, Pessah IN, et al. Mutational analysis of putative calcium binding motifs within the skeletal ryanodine receptor isoform, RYR1. J Biol Chem, 2004, 279: 53028-53035.
  • 9Nelson TE. Malignant hyperthermia: a pharmacogenetic disease of Ca^2+ regulation proteins. Current molecular medicine, 2002, 2: 347- 369.
  • 10Brooksbank RL, Badenhorts ME, lsaacs Hyam,et al. Treatment of normal skeletal muscle with FK506 or rapamycin results in halothane-induced muscle contracture. Anesthesiology, 1998, 89: 693-698.

共引文献10

同被引文献30

  • 1沈波,张薇.持续性肾脏替代治疗抢救横纹肌溶解急性肾功能衰竭[J].中国危重病急救医学,2005,17(10):637-638. 被引量:26
  • 2秦北宁,孙永利,马丽,张会,白莉华.以发热待查为表现的亚急性甲状腺炎13例分析[J].现代中西医结合杂志,2006,15(7):938-938. 被引量:8
  • 3王颖林,郭向阳,罗爱伦.我国大陆恶性高热病例的分析[J].中华麻醉学杂志,2006,26(2):107-109. 被引量:45
  • 4刘俊杰,赵俊著.现代麻醉学[M].2版.北京:人民卫生出版社,2003:36.
  • 5Es Halsall P J, Philip M. Malignant hyperthermia[J]. Br J Anaesth,2003,12( 3 ) : 5.
  • 6于进祥,李祥霞.少量非去极化肌松剂预防琥珀胆碱所致肌震颤35例观察[J].武警医学,2000,11(6):342.
  • 7Anetseder M, Hager M, Muller CR, et al. Diagnosis of susceptibility to malignant hyperthermia by use of a meta- bolic test [J]. Lancet, 2002,359 (18) : 1 579.
  • 8Amin K,Kauffman CA. Fever of unknown origin: a strategic approach to this diagnostic dilemma [ J ]. Postgrad Med, 2003, 114(3) :69-75.
  • 9Hirschmann JV. Fever of unknown origin in adults[ J]. Clin Infeet Dis, 1997,24( 3 ) :291-302.
  • 10Shiohara T,Kano Y,Takahashi R,et al. Drug-induced hypersensitivity syndrome: recent advances in the diagnosis, pathogenesis and management[J]. Chem Immunol Allergy, 2012,97:122-138.

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