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补阳还五汤治疗心脑血管病ApoE、NO水平变化及保护血管内皮的探讨 被引量:13

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摘要 目的:观察补阳还五汤对心脑血管病患者治疗前后血循环内皮细胞(CEC)计数、ApoE、NO水平变化及血管内皮损伤的关系,以探讨其作用机制和保护血管内皮的作用。方法:将300例心脑血管病患者,随机分为服用补阳还五汤治疗组(A组)150例、对照组(B组)150例。结果:治疗组(A组)服用补阳还五汤治疗后CEC计数、ApoE水平较治疗前明显下降,NO明显升高,治疗前后相比,差别有统计学意义(P<0.05)。与B组比较,差异有统计学意义。直线相关分析显示ApoE与CEC计数呈正相关,与NO呈负相关。结论:补阳还五汤可使血浆CEC计数、ApoE水平降低,NO水平升高,对心脑血管病患者血管内皮细胞具有明显的保护作用,中西医结合治疗心脑血管病有很好疗效。
出处 《中国当代医药》 2010年第6期92-93,共2页 China Modern Medicine
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