超声造影在附件区肿块良恶性鉴别诊断中的应用

Application of Contrast-enhanced Ultrasound in Discrimination of Malignant from Benign Adnexal Masses

目的：探讨目前国内外在应用超声造影鉴别诊断附件区肿块良恶性方面的研究进展。方法：查阅PubMed、CNKI数据库中关于超声造影鉴别诊断附件区肿块良恶性的研究文献，进行归纳总结分析。结果：超声造影能够显示肿瘤的异常血管和血供模式，附件区良恶性肿瘤间血供丰富程度、充盈方式及时间--强度曲线定量参数等具显著差异，较早期的恶性肿瘤即可显示恶性造影特征。结论：超声造影能够较好的鉴别诊断附件区肿块的良恶性，并可诊断早期的恶性肿瘤，值得进一步深入研究和推广应用。

Objective：To review the research advancement on discrimination of malignant from benign adnexal masses by using Contrast - enhanced Ultrasound. Methods：To consult the relevant references from PubMed and CNKI database, which concerning differentiation of malignant from benign adnexal masses by using contrast - enhanced ultrasound. Results： Contrast - enhanced ultrasound could reveal abnormal blood vessels and pattern of blood supply for tumors. There are significant differences between malignant and benign tumor in vascular density, perfusion pattern and parameters of time -intensity curve. Early malignant tumors could show specific visualization. Conclnsions： Contrast -enhanced ultrasound significantly promote the differentiation of malignant from benign adnexal tumors, it could diagnose some incipient malignant tumors by distinctive imaging. Further study and spreading its clinical application are need.