内镜下组织粘合剂注射联合套扎治疗食管胃底静脉曲张破裂出血的疗效观察

Combination of endoscopic tissue adhesive injection and variceal ligation in esophageal and gastric varices bleeding

目的评价急诊内镜下组织粘合剂（α-氰丙烯酸烷基脂）注射联合套扎治疗食管胃底静脉曲张破裂出血的临床疗效。方法2008年1月至2009年1月间21例食管胃底静脉曲张破裂出血患者接受急诊内镜下胃底曲张静脉组织粘合剂注射联合食管曲张静脉套扎（EVL）治疗，对其治疗疗效进行回顾性分析。结果21例患者的急诊止血有效率达95％（20／21），未出现严重并发症。结论急诊内镜下组织粘合剂注射联合套扎治疗食管胃底静脉曲张破裂出血，止血疗效确切，并发症发生率低，值得推广。

Objective To evaluate the clinical efficacy of emergent endoscopic injection of tissue adhesive （N-oclyl-a-cyanoacrylate） combined with endoscopic variceal ligation （EVL） for esophageal and gastric wlrices bleeding. Methods Data of 21 patients with acute esophageal and gastric variees bleeding who received emergent endoscopic injection of tissue adhesive and EVL were retrospectively studied. Results The instant hemostatic rate was 95% （20/21） with no severe complications. Conclusion Emergent en- doscopic injection of tissue adhesive combined with EVL is an effective and safe therapy for esophageal and gastric varices bleeding.