不明原因智力低下学生弓形虫感染的调查

Investigation on Toxoplasma Infection in Pupils with Undecided Pathogeny Mental Retardation

采用ＥＬＩＳＡ方法，对６６例不明原因的先天智力低下学生及３４例健康人进行了弓形虫循环抗原（ＣＡｇ）、ＩｇＭ和ＩｇＧ的检测。智力低下组弓形虫ＣＡｇ、ＩｇＭ和ＩｇＧ的阳性率分别为１６６７％（１１／６６），１９７０％（１３／６６），３７．８８％（２５／６６）；对照组弓形虫ＣＡｇ、ＩｇＭ和ＩｇＧ的阳性率分别是２９４％（１／３４），２．９４％（１／３４），１１．７６％（４／３４）。结果显示，智力低下组弓形虫感染率与对照组有显著性差异。提示在不明原因的智力低下学生中弓形虫感染较高。

In order to study and analyse toxoplasma infection in pupils with the undecided pathogeny mental retardation,the ELISA methods were used to examine serum toxoplasma circulating antigen,antibody IgM and IgG in 66 pupils with mental retardation and 34 healthy men.The results showed that the positive rates of CAg,antibody IgM and IgG in 66 cases were respectively 16.67%(11/66),19.70%(13/66),37.88%(25/66);the positive rates of CAg,IgM and IgG in healthy men were respectively 2.94%(1/34),2.94%(1/34),11.76%(4/34).There was apparent difference of toxoplasma infection between congenital mental retardation pupils and healthy men.We propose toxoplasma CAg and antibody should be examined in undecided pathogeny mental retardation pupils.