摘要
选取新发宫颈癌患者１００例及宫颈正常者１００例作为研究对象，取其宫颈分泌物作标本，用多聚酶链反应（ＰＣＲ）进行沙眼衣原体（Ｃｔ）检测，同时对所有研究对象进行有关因素的流行病学调查。结果发现，宫颈癌组Ｃｔ感染率为２８％，明显高于对照组（６％）（Ｐ＜０．０１）。利用非条件Ｌｏｇｉｓｔｉｃ回归模型进行单因素分析，筛选出１４个有意义的因素。多因素分析结果显示，初婚年龄、痛经、初孕流产、爱人婚外性生活史。
We carried out a case control study on 100 cases of cervical cancer and 100 health controls.The specimen of endocervical samples which were collected from all 200 women were detected for Ct by Polymerase Chain Reaction (PCR).Meanwhile relative risk factors were surveyed.The result showed that Ct infection rate of cases (28%) was significantly higher than the controls (6%) ( P <0.01).By means of non conditional logistic regression analysis,univariate analysis results showed 14 risk factors for cervical cancer.Multivariate analysis showed that age of first coitus、dysmenorrhea、miscarriage in first pregnancy、number of sex partners of husband、Ct infection and education of husband were the main risk factors for cervical cancer.
出处
《哈尔滨医科大学学报》
CAS
1998年第6期419-423,共5页
Journal of Harbin Medical University
基金
黑龙江省教委资助
关键词
宫颈癌
沙眼衣原体
PCR
Cervical cancer
Chlamydia trachomatis
PCR
